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A novel variant in the gene in a large Chinese family with a unique phenotype of Clouston syndrome

Frontiers of Medicine 2023, Volume 17, Issue 2,   Pages 330-338 doi: 10.1007/s11684-022-0933-2

Abstract: To date, four mutations in the <i>GJB6i> gene, G11R, V37E, A88V, and D50N, have been confirmed to causeIn previous studies, the focus has been mainly on gene sequencing, and there has been a lack of research

Keywords: Clouston syndrome     whole exome sequencing     <i>GJB6i> gene     novel variant     unique phenotype    

Association of gene variants with juvenile amyotrophic lateral sclerosis

Frontiers of Medicine doi: 10.1007/s11684-023-1005-y

Abstract: A variation within <i>TRMT2Bi> (c.1356G>T; p.K452N) was identified to be associated with ALS in a familya high level of ROS were observed functionally in patient-originated lymphoblastoid cell lines and <i>TRMT2Bi> interfering HEK293 cells.Further, <i>TRMT2Bi> variations overexpression cells also displayed decreased ND1.In conclusion, a novel JALS-associated gene called <i>TRMT2Bi> was identified, thus broadening the

Keywords: <i>TRMT2Bi>     amyotrophic lateral sclerosis     mitochondrial complex I     tRNA methylation     reactive oxygen    

High frequency of alternative splicing variants of the oncogene in neuroendocrine tumors of the pancreas and breast

Frontiers of Medicine   Pages 907-923 doi: 10.1007/s11684-023-1009-7

Abstract: that Box 6/Box 7-containing <i>FAKi> variants (<i>FAKi><i>6/7i>) were observed in 7, and found that <i>FAKi><i>6/7i> was positive in 34 (75.6%) of 45 pancreaticthat <i>FAKi><i>6/7i> was positive in 14 (93.3%) of 15 BrNECs but 0of <i>FAKi><i>6/7i> in cells.These results suggested that <i>FAKi><i>6/7i> could be a biomarker of NENs and represent

Keywords: <i>FAKi><i>6/7i>     SRRM4     neuroendocrine neoplasms     pancreas     breast    

Gene delivery into isolated

Nan Zheng, Ziyuan Song, Yang Liu, Lichen Yin, Jianjun Cheng

Frontiers of Chemical Science and Engineering 2017, Volume 11, Issue 4,   Pages 521-528 doi: 10.1007/s11705-017-1612-8

Abstract: The application of gene delivery materials has been mainly focused on mammalian cells while rarely extendedThis study therefore widens the utilities of helical polypeptide as a unique category of gene deliverymaterials, and may find their promising applications toward plant gene delivery.

Keywords: <ii>-helical polypeptide     plant gene delivery     protoplast     intact leaves     transfection    

A novel aldo-keto reductase gene,

Jinxi HUO, Bing DU, Sifan SUN, Shaozhen HE, Ning ZHAO, Qingchang LIU, Hong ZHAI

Frontiers of Agricultural Science and Engineering 2018, Volume 5, Issue 2,   Pages 206-213 doi: 10.15302/J-FASE-2018225

Abstract: In this study, the gene was isolated from sweet potato.

Keywords: cadmium stress     <i>IbAKRi>     <i>Ipomoea batatasi>     sweet potato    

Distinct gene expression pattern of mutations coordinated by target repression and promoter hypermethylation

Frontiers of Medicine 2022, Volume 16, Issue 4,   Pages 627-636 doi: 10.1007/s11684-020-0815-4

Abstract: However, <i>RUNX1i> mutations have been largely under-explored compared with <i>RUNX1i> fusions mainlyi> mutations in AML./i> mutations.Then, based on RNA-seq data from The Cancer Genome Atlas AML cohort, we developed a 300-gene signatureThis study revealed the distinct gene expression pattern of <i>RUNX1i> mutations and the underlying

Keywords: <i>RUNX1i>     gene mutation     acute myeloid leukemia     transcriptional repression     DNA methylation    

<i>NES1i>/<i>KLK10i> and <i>hNISi> gene therapy enhanced iodine-131 internal radiation in PC3 proliferation

Jiajia Hu, Wenbin Shen, Qian Qu, Xiaochun Fei, Ying Miao, Xinyun Huang, Jiajun Liu, Yingli Wu, Biao Li

Frontiers of Medicine 2019, Volume 13, Issue 6,   Pages 646-657 doi: 10.1007/s11684-018-0643-y

Abstract: gene is thought to be a tumor-suppressor gene.Thus, we supposed to have an “enhanced firepower” effect by combining overexpressed gene therapy andI radiation therapy uptake by overexpressed hNIS protein.therapy and I radiation therapy mediated by overexpressed hNIS protein had the best tumor proliferativethat via inhibition of expression, overexpressed might enhance the effect of radiation therapy of I

Keywords: androgen-independent prostate cancer     normal epithelial cell-specific 1/kallikrein 10     sodium/iodide symporter     radiation therapy     proliferation    

<i>RR1i> and <i>RR2i> gene deletion affects the immunogenicity of a live attenuated pseudorabies

Shijun YAN,He YAN,Chaolin ZHANG,Tongyan WANG,Qingyuan YANG,Zhe SUN,Yan XIAO,Feifei TAN,Xiangdong LI,Kegong TIAN

Frontiers of Agricultural Science and Engineering 2016, Volume 3, Issue 1,   Pages 81-86 doi: 10.15302/J-FASE-2016088

Abstract: In this study, we deleted and genes based on a / / triple gene-deleted pseudorabies virus and tested

Keywords: pseudorabies virus     <i>RR1i> and <i>RR2i>     ribonucleotide reductase     vaccine candidate    

Anefficient data layout scheme for better I/O balancing inRAID-6 storage systems

Ping XIE,Jian-zhong HUANG,Er-wei DAI,Qiang CAO,Chang-sheng XIE

Frontiers of Information Technology & Electronic Engineering 2015, Volume 16, Issue 5,   Pages 335-345 doi: 10.1631/FITEE.1400362

Abstract: Among redundant arrays of independent disks (RAID)-6 codes, maximum distance separable (MDS) based RAID-6 codes are popular because they have the optimal storage efficiency.vertical MDS codes exhibit better load balancing compared to horizontal MDS codes in partial stripes, an I/Os among P-coded disk arrays (i.e., PC).particular, in the case of a 12-disk array, the UPC scheme can improve the access performance of the RAID-6

Keywords: RAID-6     Data availability     High performance     I/O balancing    

effect of sodium perfluorononyloxy-benzenesulfonate on in aerobic denitrification, cell structure and gene

Frontiers of Environmental Science & Engineering 2021, Volume 15, Issue 5, doi: 10.1007/s11783-021-1391-9

Abstract:

• OBS inhibited the growth of <i>P. stutzerii> and destroyed its structure

Keywords: Sodium perfluorononyloxy-benzenesulfonate     Aerobic denitrification     <i>Pseudomonas stutzerii>     Ecotoxicity    

The Potential Role of Powdery Mildew-Resistance Gene <i>Pm40i> in Chinese Wheat-Breeding Programs inthe Post-<i>Pm21i> Era Perspective

Shengwen Tang,Yuting Hu,Shengfu Zhong,Peigao Luo

Engineering 2018, Volume 4, Issue 4,   Pages 500-506 doi: 10.1016/j.eng.2018.06.004

Abstract: Powdery mildew-resistance (Pm) gene Pm21 was first transferred into wheat in the 1980s, by translocating the Heuchera villosa chromosome arm 6VS to the wheat chromosome arm 6AL (6VS·6AL).

Keywords: Wheat     Powdery mildew     <i>Pm21i>     <i>Pm40i>     Alien species     Native resistance    

Fusaricidins in

Weicheng LIU, Xiaoli WU, Xuelian BAI, Hong ZHANG, Dan DONG, Taotao ZHANG, Huiling WU

Frontiers of Agricultural Science and Engineering 2018, Volume 5, Issue 2,   Pages 262-270 doi: 10.15302/J-FASE-2017166

Abstract: The fusaricidins biosynthetic gene cluster (BGC) from A21 was cloned by PCR and comparative cluster analysisrevealed that gene , the 3′ boundary of the fusaricidin BGC in strain PKB1, was not present in fusaricidin

Keywords: antifungal activity     biosynthetic gene cluster     <i>Botrytis cinereai>     fusaricidin     <i>Paenibacillus polymyxai>    

a novel K+ transporter gene in cotton

Yiru WANG, Juan XU, Mingcai ZHANG, Xiaoli TIAN, Zhaohu LI

Frontiers of Agricultural Science and Engineering 2018, Volume 5, Issue 2,   Pages 226-235 doi: 10.15302/J-FASE-2017170

Abstract: This study, identified a K transporter gene, expressed in the roots of cotton ( ) cv.

Keywords: cotton     <i>GhKT2i>     potassium     transporter     uptake    

Morphology selective construction of

Maher Darwish, Ali Mohammadi, Navid Assi, Samer Abuzerr, Youssef Alahmad

Frontiers of Chemical Science and Engineering 2020, Volume 14, Issue 4,   Pages 561-578 doi: 10.1007/s11705-019-1808-1

Abstract: Controlled growth of Bi WO nanorods with exposed [0 0 1] facets and the fabrication of an Fe O -Bi WO magnetic composite by a microwave-assisted polyol process, were achieved in this study. The adsorptivity and photocatalytic performance of the composite toward sunset yellow dye degradation were greatly enhanced by the -cyclodextrin cavities on its surface, firmly anchored through a cetyltrimethylammonium bromide linkage. A series of examinations and characterizations were carried out to determine the influence of various factors on the morphological modulation-photocatalytic behavior of the pure Bi WO prior to final functionalization. Changing the pH of the precursor solution impacted the formation of 0D, 2D, and 3D structures; however, the presence of hexamethylenetetramine surfactant induced the development of 1D nanorod structure. A reasonable crystal growth mechanism was proposed to elucidate the formation process. Conversely, the mechanism of the activity enhancement of -cyclodextrin functionalized Fe O -Bi WO , compared to that of the non-functionalized samples, could be realized with the assistance of chemical trapping experiments on sunset yellow, and was confirmed on the colorless antibiotic (sulfamethoxazole). The high performance and durability of this composite can be attributed to the facet-dependent activity, large adsorption capacity due to inclusion interactions, enhanced visible light absorption, and efficient charge separation.

Keywords: <ii>-cyclodextrin     Bi2WO6     shape controlled     nanorod     sunset yellow    

A PLATFORM TO AID SELECT THE OPTIMAL TOOL TO DESIGN GUIDE RNAS

Frontiers of Agricultural Science and Engineering   Pages 296-305 doi: 10.15302/J-FASE-2022479

Abstract:

● Summaries on sgRNAs design.

Keywords: CRISPR/Cas     <i>Aid-TGi>     gene editing     sgRNA design     web server    

Title Author Date Type Operation

A novel variant in the gene in a large Chinese family with a unique phenotype of Clouston syndrome

Journal Article

Association of gene variants with juvenile amyotrophic lateral sclerosis

Journal Article

High frequency of alternative splicing variants of the oncogene in neuroendocrine tumors of the pancreas and breast

Journal Article

Gene delivery into isolated

Nan Zheng, Ziyuan Song, Yang Liu, Lichen Yin, Jianjun Cheng

Journal Article

A novel aldo-keto reductase gene,

Jinxi HUO, Bing DU, Sifan SUN, Shaozhen HE, Ning ZHAO, Qingchang LIU, Hong ZHAI

Journal Article

Distinct gene expression pattern of mutations coordinated by target repression and promoter hypermethylation

Journal Article

<i>NES1i>/<i>KLK10i> and <i>hNISi> gene therapy enhanced iodine-131 internal radiation in PC3 proliferation

Jiajia Hu, Wenbin Shen, Qian Qu, Xiaochun Fei, Ying Miao, Xinyun Huang, Jiajun Liu, Yingli Wu, Biao Li

Journal Article

<i>RR1i> and <i>RR2i> gene deletion affects the immunogenicity of a live attenuated pseudorabies

Shijun YAN,He YAN,Chaolin ZHANG,Tongyan WANG,Qingyuan YANG,Zhe SUN,Yan XIAO,Feifei TAN,Xiangdong LI,Kegong TIAN

Journal Article

Anefficient data layout scheme for better I/O balancing inRAID-6 storage systems

Ping XIE,Jian-zhong HUANG,Er-wei DAI,Qiang CAO,Chang-sheng XIE

Journal Article

effect of sodium perfluorononyloxy-benzenesulfonate on in aerobic denitrification, cell structure and gene

Journal Article

The Potential Role of Powdery Mildew-Resistance Gene <i>Pm40i> in Chinese Wheat-Breeding Programs inthe Post-<i>Pm21i> Era

Shengwen Tang,Yuting Hu,Shengfu Zhong,Peigao Luo

Journal Article

Fusaricidins in

Weicheng LIU, Xiaoli WU, Xuelian BAI, Hong ZHANG, Dan DONG, Taotao ZHANG, Huiling WU

Journal Article

a novel K+ transporter gene in cotton

Yiru WANG, Juan XU, Mingcai ZHANG, Xiaoli TIAN, Zhaohu LI

Journal Article

Morphology selective construction of

Maher Darwish, Ali Mohammadi, Navid Assi, Samer Abuzerr, Youssef Alahmad

Journal Article

A PLATFORM TO AID SELECT THE OPTIMAL TOOL TO DESIGN GUIDE RNAS

Journal Article